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What is Nucleofill?

Nucleofill is a polynucleotide-based injectable gel specifically designed for skin rejuvenation and protection. Its high levels of viscosity allow for long lasting healing of wounds and deep skin repair.

Like Rejuran Healer, Nucleofill also contains polynucleotides derived from salmon DNA. However, Nucleofill has a higher concentration of PN and is hence very suitable for those with damaged skin, pigmentation and scarring.

Nucleofill is prized for: 

  • Regeneration of skin
  • Increasing circulation of cells and removing free radicals, promoting a cleansing effect
  • Deep moisturising effect
  • Contouring and firming skin

How is Nucleofill different from Rejuran Healer?

While both Nucleofill and Rejuran Healer contain the same substance—polynucleotides derived from Salmon DNA— the newcomer Nucleofill has the following improvements:


Rejuran Healer Nucleofill (Strong)
– Concentration of 2% – Higher Concentration of 2.5%
– 2ml per syringe – 1.5ml per syringe
– Beehive injection style of around 100 injection points – Only 5 injection points
– Lower spreadability compared to Nucleofill even though the same technique is possible     – Better spreadability in the skin, which achieves better results with the 5-BAP technique
– Lower PH value – Higher PH value that eases discomfort during injection

For those who have a lower pain threshold, the lower acidity level of Nucleofill in combination with the significantly fewer injection points can make a world of difference in comfort level between Rejuran and Nucleofill.


How Does Nucleofill Work?

Nucleofill achieves biostimulation of the skin in three ways:

  1. Moisturising effect

Nucleofill contains high molecular weight polynucleotide chains, meaning it is capable of retaining a considerable amount of water molecules. As such, Nucleofill has intense hydrating properties, which is key for anyone looking for younger, refreshed skin.

  1. Free radical scavenging effect

Free radicals are unstable molecules that damage your skin cells. Nucleofill’s polymeric chemical structure blocks free radicals and act as immediate “scavengers” against free radicals.

  1. Biostimulating effect

Nucleofill contains biostimulation properties and increases the production of Type 1 Collagen. This stimulation is slow and continuous, and is what gives patients a long-lasting tissue lift.

Benefits of Nucleofill

  • Lifts sagging skin
  • Strengthens sensitive and stressed out skin
  • Improves the appearance of scars and stretch marks
  • Hydrates and repairs dry and damaged skin
  • Improves the appearance of pigmentation
"Everyone’s face ages differently. We recommend Nucleofill for patients looking to rejuvenate their skin due to uneven skin texture caused by acne scars or early signs of ageing. Our doctors at Veritas Medical Aesthetics provide customised protocols for patients who may experience facial ageing more severely in some parts of the face, and may combine other skinbooster injectable treatments to target the different concerns of the face, maximising results."

As the pioneer of the LDM Ultrasound technology in Singapore, Dr Chua offers a combination of LDM ultrasound treatment with skinbooster injections to optimise the results of the skinbooster and minimise any downtime. This helps our patients to get the most out of their skinbooster.


How many treatment sessions do I need?

How many injection sites are there?

How long do results last?

What is the downtime?

How much does Nucleofill cost in Singapore?

Who is Nucleofill suitable for?


13 Stamford Rd,
#B2-35 Capitol Singapore,
Singapore 178905


Mon to Fri: 11am - 8pm
Sat: 11am - 6pm
PH: By appointment only.

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